Monday, February 25, 2008

Feb. 27th (Wed.)

On Wednesday, Feb. 27th, starting at Noon in CCSR 4105, Roopa B. (Steinman Lab) will present:

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

Ingunn M Stromnes, Lauren M Cerretti, Denny Liggitt, Robert A Harris & Joan M Goverman.

Published online: 17 February 2008; | doi:10.1038/nm1715


Link to article: click here

Tuesday, February 19, 2008

Feb. 20th (Wed.)

On Wednesday, Feb. 20th, starting at Noon in CCSR 4105, Tin M. (Chen Lab) will present:

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

Hsu HC, Yang P, Wang J, Wu Q, Myers R, Chen J, Yi J, Guentert T, Tousson A, Stanus AL, Le TV, Lorenz RG, Xu H, Kolls JK, Carter RH, Chaplin DD, Williams RW, Mountz JD.

Nat Immunol. 2008 Feb;9(2):166-75.


Link to article: click here

Monday, February 11, 2008

Feb. 13th (Wed.)

On Wednesday, Feb. 13th, starting at Noon in CCSR 4105, Crystal B. (Lewis Lab) will present:

Novel cell death program leads to neutrophil extracellular traps

Tobias A. Fuchs, Ulrike Abed, Christian Goosmann, Robert Hurwitz, Ilka Schulze, Volker Wahn, Yvette Weinrauch, Volker Brinkmann, and Arturo Zychlinsky

J. Cell Biol. 2007 176: 231-241.

Link to article: click here

Also, Crystal has included a review article relevant to the research article: click here

***
From Crystal:

Attached is the journal club article that I picked for next week (Fuchs et al., 2007). The article is about neutrophils and their ability to make NETs (Neutrophil Extracellular Traps). The paper has some every nice time-lapse microscopy experiments of the neutrophils making the NETs and shows that NETs depend on the generation of reactive oxygen species (ROS) by NADPH oxidase. The second article (Brinkmann and Zychlinsky) is a recent review article which gives an overview of what is known about NETs and discusses their diverse roles in infection including cystic fibrosis and systemic lupus erythematosis.

Monday, February 4, 2008

Feb. 6th (Wed.)

On Wednesday, Feb. 6th, starting at Noon in CCSR 4105, Chih L. (Utz/Gozani Labs) will present:

Developmental switch of intestinal antimicrobial peptide expression

Sandrine Ménard, Valentina Förster, Michael Lotz, Dominique Gütle, Claudia U. Duerr, Richard L. Gallo, Birgitta Henriques-Normark, Katrin Pütsep, Mats Andersson, Erik O. Glocker, and Mathias W. Hornef

The Journal of Experimental Medicine, Vol. 205, No. 1, 183-193.

Link to article: click here