Feb. 13th (Wed.)

On Wednesday, Feb. 13th, starting at Noon in CCSR 4105, Crystal B. (Lewis Lab) will present:

Novel cell death program leads to neutrophil extracellular traps

Tobias A. Fuchs, Ulrike Abed, Christian Goosmann, Robert Hurwitz, Ilka Schulze, Volker Wahn, Yvette Weinrauch, Volker Brinkmann, and Arturo Zychlinsky

J. Cell Biol. 2007 176: 231-241.

Link to article: click here

Also, Crystal has included a review article relevant to the research article: click here

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From Crystal:

Attached is the journal club article that I picked for next week (Fuchs et al., 2007). The article is about neutrophils and their ability to make NETs (Neutrophil Extracellular Traps). The paper has some every nice time-lapse microscopy experiments of the neutrophils making the NETs and shows that NETs depend on the generation of reactive oxygen species (ROS) by NADPH oxidase. The second article (Brinkmann and Zychlinsky) is a recent review article which gives an overview of what is known about NETs and discusses their diverse roles in infection including cystic fibrosis and systemic lupus erythematosis.