Wednesday, June 17, 2009

This week's journal club presentation will be given by Serge Emaleu (Herzenberg lab). Serge will be discussing "HIV Research in Africa".

We will be in MSOB X303, 12:00-1:00pm (Wed. June 17th).

Wednesday, June 10, 2009

This week's journal club presentation will be given by Linh Nguyen. Wed. June 10th, MSOB X303, 12:00-1:00pm.

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A protective function for interleukin 17A in T cell–mediated intestinal inflammation
William O'Connor Jr, Masahito Kamanaka, Carmen J Booth, Terrence Town, Susumu Nakae, Yoichiro Iwakura, Jay K Kolls & Richard A Flavell
Nature Immunology 10, 603 - 609 (2009)

Link to paper

Wednesday, May 13, 2009

This week's journal club presentation will be given by Crystal Botham (Lewis lab). We will be in CCSR 3226 (12:00-1:00pm).

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Palsson-McDermott EM, Doyle SL, McGettrick AF, Hardy M, Husebye H, Banahan K, Gong M, Golenbock D, Espevik T, O'Neill LA.
Nat Immunol. 2009 May 3. [Epub ahead of print]

Link to paper

Wednesday, May 6, 2009

This week's journal club presentation will be given by Patricia Sadate-Ngatchou (Herzenberg lab). We will be in MSOB X303 (12:00-1:00pm).

Pat will be discussing the following paper:

A differentiation pathway for B1 cells in adult bone marrow.
Esplin BL, Welner RS, Zhang Q, Borghesi LA, Kincade PW.
Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5773-8. Epub 2009 Mar 23.

Link to paper

Wednesday, April 29, 2009

This week's journal club presentation will be given by Fred Elfman (Nolan lab).

Wednesday, January 14, 2009

This week's journal club presentation will be given by Jack Lin (Fathman lab).

Memory CD8 T-cell compartment grows in size with immunological experience.
Vezys V, Yates A, Casey KA, Lanier G, Ahmed R, Antia R, Masopust D.
Nature. 2009 Jan 8;457(7226):196-9.

Link to paper

Wednesday, January 7, 2009

Happy 2009! This week's presentation will be given by Jonathan Rothbard. Jonathan will be discussing "The Dance between Academia and Biotech".


Please note, we are in the normal room (CCSR 4205), but we have a new time slot (12:00 - 1:00pm).

December 10, 2008

This week's journal club presentation will be given by Robert Axtell (Steinman lab). We will be in CCSR 4205 (12:30 - 1:30pm) Wed. Dec. 10th. This will be the final journal club presentation this year - journal club will resume on January 7th 2009.

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway.
Cao W, Manicassamy S, Tang H, Kasturi SP, Pirani A, Murthy N, Pulendran B.
Nat Immunol. 2008 Oct;9(10):1157-64.

Link to paper.

And the corresponding News & Views:
RAPping production of type I interferon in pDCs through mTOR.
Costa-Mattioli M, Sonenberg N.
Nat Immunol. 2008 Oct;9(10):1097-9.

Link to paper.

December 3, 2008

This week's journal club presentation will be given by Shannon Dunn (Steinman lab). We will be in CCSR 4205 (12:30 - 1:30pm). Shannon will be discussing two back to back papers published in Nature Immunology that describe a new IL-9 producing T helper subset.

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.
Veldhoen M, Uyttenhove C, van Snick J, Helmby H, Westendorf A, Buer J, Martin B, Wilhelm C, Stockinger B.
Nat Immunol. 2008 Dec;9(12):1341-6.
Link to paper

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells.
Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK.
Nat Immunol. 2008 Dec;9(12):1347-55.

Link to paper

November 12, 2008

This week's presentation will be given by Lee Herzenberg. Lee will be discussing "Unpopular Ideas in Science".

Please note, we are back in the normal room (CCSR 4205, 12:30 - 1:30pm).

November 5, 2008

This week's journal club presentation will be given by Archana Iyer (Galli lab). Please note the room change: we will be in MSOB X303 (12:30 - 1:30pm). The paper selected is:

CTLA-4 Control over Foxp3+ Regulatory T cell Function.

Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, Tomoyuki Yamaguchi, Makoto Miyara, Zoltan Fehevari, Takashi Nomura, & Shimon Sakaguchi

Science. 2008 Oct; 322: 271-275.

Link to paper

October 29, 2008

This week's journal club presentation will be given by Remi Creusot (Fathman Lab). Please note the room change: we will be in MSOB X303 (12:30 - 1:30pm). 

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.

Nedjic J, Aichinger M, Emmerich J, Mizushima N, Klein L.

Nature. 2008 Sep 18;455(7211):396-400.

Link to paper

October 22, 2008

This week's journal club presentation will be given by Jun Seita (Weissman Lab). We will be in CCSR 4205 (12:30 - 1:30pm).

Jun's talk is titled:

"Quantitative Analysis of Microarray Data based on Dynamic-range Database"

October 15, 2008

This week's journal club presentation will be given by Jason Ptacek (Nolan lab). We will be in CCSR 4205 (12:30 - 1:30pm).

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis.

Neubert K, Meister S, Moser K, Weisel F, Maseda D, Amann K, Wiethe C, Winkler TH, Kalden JR, Manz RA, Voll RE.

Nat Med. 2008 Jul;14(7):748-55.

Link to paper

October 8, 2008

This week's journal club presentation will be given by Janet Kalesnikoff. Please note the new room (CCSR 4205) and time (12:30 - 1:30pm).

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense.

Shida Yousefi, Jeffrey A Gold, Nicola Andina, James J Lee, Ann M Kelly, Evelyne Kozlowski, Inès Schmid, Alex Straumann, Janine Reichenbach, Gerald J Gleich & Hans-Uwe Simon

Nat Med. 2008 Sept;14(9):949-53.

Link to article: click here

September 24, 2008

Yannick Pouliot, Ph.D., MBA from Lane Library will be giving a talk entitled "3 things you do not want to do without."

Off until Fall

Thank you for your participation in the successful 2007-2008 Postdoctoral Immunology Journal Club!

We will resume again in the Fall for the 2008-2009 academic calendar.

Have a great Summer,
Jack

June 18th (Wed.)

On Wednesday, June 18th, starting at Noon in CCSR 4105, Mark D. will present:

"Navigating Contemporary Immunology"

Two selected readings (downloads as Adobe .pdf files):

How to ask questions

Hegemony of Mediocrity

June 11th (Wed.)

On Wednesday, June 11th, starting at Noon in CCSR 4105, Gerald C. will present:

"How to Read a Scientific Paper"

(With selected illustrative sample papers.)




Crabtree Lab

June 4th (Wed.)

On Wednesday, June 4th, starting at Noon in CCSR 4105, Shigeru O. will present:

Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics.

Caleb J. Bashor, Noah C. Helman, Shude Yan, Wendell A. Lim.

Science 14 March 2008: Vol. 319. no. 5869, pp. 1539 - 1543.

Link to article: click here